(2/6)-(10/6)

Use the site calculator:

http://web2.0calc.com/

$$\left({\frac{{\mathtt{2}}}{{\mathtt{6}}}}\right){\mathtt{\,-\,}}\left({\frac{{\mathtt{10}}}{{\mathtt{6}}}}\right) = {\mathtt{\,-\,}}{\frac{{\mathtt{4}}}{{\mathtt{3}}}} = -{\mathtt{1.333\: \!333\: \!333\: \!333\: \!333\: \!3}}$$

Or do it by hand--your choice:

(2/6) = (1/3)

(10/6)=(5/3)

(1/3)-(5/3)

= (-4/3)

Thanks Kitty :)