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A patient is administered 300 mg of a certain drug every 3 hours. The half-life of the drug in the body is 188.4 minutes. Determine the amount of drug that remains immediately after the patient takes the th dose.

 Nov 12, 2014

Best Answer 

 #1
avatar+23254 
+5

I'm assuming that you meant "takes the third dose".

Formula for half-life:  F  =  I·(½)^(t/h)

F = final amount          I = initial amount         t = time         h = half-life 

The second dose will be taken 3 hours after the first dose and the third dose will be taken 6 hours after the first dose.

For the initial 300 mg dose after 6 hours (360 minutes):  F  =  300·(½)^(360/188.4)  =  79.78 mg

For the second 300 mg dose after 3 hours (180 mins):    F  =  300·(½)^(180/188.4)  =  154.71 mg

For the third dose (just taken):  F  =  300 mg.

Total:  79.78 mg + 154.71 mg + 300 mg  =  534.49 mg

 Nov 12, 2014
 #1
avatar+23254 
+5
Best Answer

I'm assuming that you meant "takes the third dose".

Formula for half-life:  F  =  I·(½)^(t/h)

F = final amount          I = initial amount         t = time         h = half-life 

The second dose will be taken 3 hours after the first dose and the third dose will be taken 6 hours after the first dose.

For the initial 300 mg dose after 6 hours (360 minutes):  F  =  300·(½)^(360/188.4)  =  79.78 mg

For the second 300 mg dose after 3 hours (180 mins):    F  =  300·(½)^(180/188.4)  =  154.71 mg

For the third dose (just taken):  F  =  300 mg.

Total:  79.78 mg + 154.71 mg + 300 mg  =  534.49 mg

geno3141 Nov 12, 2014

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