Total plasma volume is important in determining the required plasma component in blood replacement therapy for a person undergoing surgery. Plasma volume is influenced by the overall health and physical activity of an individual. Suppose that a random sample of 44 male firefighters are tested and that they have a plasma volume sample mean ofx = 37.5 ml/kg (milliliters plasma per kilogram body weight). Assume that σ = 7.20 ml/kg for the distribution of blood plasma.
| lower limit | |
| upper limit | |
| margin of error |
Find the sample size necessary for a 99% confidence level with maximal error of estimate E = 2.10 for the mean plasma volume in male firefighters. (Round up to the nearest whole number.)
