What is the total of 49 1/4 + 3 3/8

To find the answer, change the fractions into whole numbers.

$$49\frac{1}{4}+3\frac{3}{8}\\\\=49\frac{2}{8}+3\frac{3}{8}$$  

Now, add the whole numbers.

$${\mathtt{49}}{\mathtt{\,\small\textbf+\,}}{\mathtt{3}} = {\mathtt{52}}$$

Now, add the fractions.

$${\frac{{\mathtt{2}}}{{\mathtt{8}}}}{\mathtt{\,\small\textbf+\,}}{\frac{{\mathtt{3}}}{{\mathtt{8}}}} = {\frac{{\mathtt{5}}}{{\mathtt{8}}}}$$

Now, combine the final answer of the fractions and whole numbers together and you get the answer  $$52\frac{5}{8}$$ .

$$\mbox{Final\;Answer}:\;52\frac{5}{8}$$

Hope it helps!