You can start by assuming that, if it factors nicely, it will be in the form
(ax + b)(cx + d) where a, b, c and d are nice whole numbers (positive or negative).
Expanding these brackets we get:
(ax + b)(cx + d) = a*c*x2 + a*d*x + b*c*x + b*d = a*c*x2 + (a*d + b*c)*x + b*d
Now compare this with the left-hand side of your equation 6x2 - 5x - 4
A. From the constant term we must have b*d = -4, so the magnitudes of b and d must be 1 and 4 or 2 and 2.
B. From the x2 term a*c = 6 so the magnitudes of a and c must be 1 and 6 or 2 and 3
C. From the x term we must have a*d + b*c = -5
Now you have to try various combinations of a, b, c and d from A and B until you get C correctly (you'll have to include the possiblity that the signs are positive or negative as well). This sounds like a lot of combinations, but actually there aren't that many to try and you'll find the right values fairly quickly.
If no combinations fit it means the equation doesn't factorize nicely and you would have to use the quadratic formula.
Alternatively, you could use the quadratic formula right away!